Table 1 Summary of baseline sample characteristicsa

From: Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment

Sample set (N)

Age (mean±s.d.)

Baseline CDR-SB (mean±s.d.a)

Baseline MMSE (mean±s.d.a)

Gender (% male)

APOE status (% ɛ4 carriers)b

ADNI (333 MCI)

75.0±7.14

1.6±0.88

27.1±1.75

64.3

54.5

Vitamin E Trial (489 MCI)

73.0±7.11

1.8±0.78

27.4±1.75

54.0

58.5

Combined (822 MCI)

73.9±7.18

1.7±0.82

27.3±1.76

58.2

57.3

GenADA (783 AD)

72.2±8.49

NA

NA

42.5

62.8

  1. Abbreviations: AD, Alzheimer's disease; ADNI, Alzheimer's Disease Neuroimaging Initiative; CDR-SB, Clinical Dementia Rating-sum of boxes; MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; NA, not applicable; s.d., standard deviation.
  2. aOnly Caucasian subjects are included in the analysis and reported here.
  3. bAPOE ɛ4 carriers include subjects with one or two copies of ɛ4 allele at the APOE locus.
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