Table 2 Functional analyses of schizophrenia susceptibility genes exhibiting differences in expression between newborn and adult monkeys in any one of five distinct hippocampal regions

From: Developmental regulation of expression of schizophrenia susceptibility genes in the primate hippocampal formation

Adult > newborn
EC	DG	CA3	CA1	Sub
Cell–cell signaling	Axogenesis	Cell–cell signaling	Cell–cell signaling	Apoptosis
Synaptic transmission	Neuron differentiation	Inflammatory response	Inflammatory response	Cell cycle
Transmission of nerve impulse	Regulation of neurotransmitter levels	Neurotransmitter transport		Cell–cell signaling
	Synaptic transmission	Response to drug		Positive regulation of transport
	Transmission of nerve impulse			Response to drug
	Vesicle-mediated transport			Response to endogenous stimulus
				Tyrosine kinase signaling pathway
Newborn > adult
Cell adhesion	Axogenesis	Apoptosis	Calcium signaling pathway	Cell adhesion
Glutamate neurotransmission	Cell adhesion	Associative learning	Cell cycle	Cell differentiation
Inflammatory response	Cell migration	Dendrite morphogenesis	Cyclic nucleotide	Cell migration monoamine
Neurotransmission	Cyclic nucleotide	G-protein signaling	Dendrite morphogenesis	Glial cell differentiation
Regulation of membrane potential	G-protein signaling	Glutamate neurotransmission	G-protein signaling	Neurogenesis response to synaptic transmission
Endogenous stimulus	Glial cell differentiation	Inflammatory response	GABA signaling pathway	Transmission of nerve impulse
Response to external stimulus	Gliogenesis	Monoamine neurotransmission	Glial cell differentiation
Response to organic nitrogen	Glutamate neurotransmission	Neurogenesis	Glutamate neurotransmission
Synaptic transmission	Lipid catabolic process	Neuron differentiation	Monoamine neurotransmission
Transmission of nerve impulse	Monoamine neurotransmission	Neuron projection	Neurogenesis
	Multicellular organismal response to stress	Nitrogen compound metabolic process	Neuron differentiation
	Neurogenesis	Notch pathway	Neuron projection
	Neuron differentiation	Regulation of membrane potential	Nitrogen compound metabolic process
	Nitrogen compound metabolic process	Synaptic plasticity	Peptidyl-tyrosine modification
	Phosphoinositide-mediated signaling	Synaptic transmission	Regulation of membrane potential
	Regulation of membrane potential	Transmission of nerve impulse	Regulation of transcription
	Response to nutrient levels	Tyrosine kinase signaling pathway	Response to drug
	Startle response		Response to organic nitrogen
	Synaptic plasticity		Startle response
	Synaptic transmission		Synaptic plasticity
	Transmission of nerve impulse		Synaptic transmission
			Transmission of nerve impulse
			Tyrosine kinase signaling pathway

DG, dentate gyrus; EC, entorhinal cortex; Sub, subiculum.Groups in bold are highlighted in the Results and Discussion sections.

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Table 2 Functional analyses of schizophrenia susceptibility genes exhibiting differences in expression between newborn and adult monkeys in any one of five distinct hippocampal regions

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