Figure 1
From: Absence of age-related prefrontal NAA change in adults with autism spectrum disorders

Location of volume of interest (VOI) and representative spectra of 3-T proton magnetic resonance spectroscopy (1H-MRS). (a) A T2-weighted brain image in orthogonal slices in a control subject. The square indicates the VOI (20 × 20 × 20 mm3) voxel in the medial prefrontal cortex, including mainly the pregenual anterior cingulate and paracingulate gyri. (b and c) Representative medial prefrontal 1H-MRS spectra of autism spectrum disorder (ASD) subject (b) or typical development (TD) subject (c) as fit by the LCModel.