Figure 2 | Translational Psychiatry

Figure 2

From: Overweight and obesity are associated with neuronal injury in the human cerebellum and hippocampus in young adults: a combined MRI, serum marker and gene expression study

Figure 2

Anatomical localization of GM density decrease accompanied with an increase of serum NSE concentration in overweight and obese subjects. Significant negative correlation between GM density and NSE was detected in hippocampal and cerebellar regions using a voxel threshold of P<0.005 and a cluster threshold of P<0.05, FDR-corrected, color coded in red/yellow. Using the SPM Anatomy toolbox, both cerebellar clusters were assigned to Lobule VIIa Crus I (Hem) (top row, color coded in red/yellow, see also Table 2). Both clusters located in the medial temporal lobe were assigned to the left and right entorhinal cortex (bottom row).

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