Figure 4 | Translational Psychiatry

Figure 4

From: Overweight and obesity are associated with neuronal injury in the human cerebellum and hippocampus in young adults: a combined MRI, serum marker and gene expression study

Figure 4

Expression of NSE in the human brain. Individually normalized gene expression is shown in Z scores normalized to whole human brain expression. (a) Heat map across the whole human brain and for each of the three subjects beside each other, where green indicates low and red high expression. For the cerebellum cortex (C) and nuclei (N) are separated. Bars represent mean normalized gene expression±s.d. across three male subjects for (b) the whole brain and (c) cerebellar sub-regions. In (a), NSE-1/NSE-2, and in (b), probe 1/probe 2 (white and black bars, respectively) represent data for the two NSE probes analyzed in the Allen Human Brain Atlas (see Materials and methods section). In (c), probes 1 and 2 are pooled. Accordingly, white and black color is only used to contrast adjacent bars here. ***P<0.001, **P<0.01, *P<0.05 one-tailed Student’s t-test against 0. Cereb: cerebellum, Form: formation, Ncl: nucleus.

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