Table 1 Demographic characteristics

From: Abnormal fatty acid composition in the frontopolar cortex of patients with affective disorders

Parameter

Control (n=15)

MDD (n=15)

BD (n=15)

Schizophrenia (n=15)

Statistical results

     

P-value

Technique

Age at death (years)

48±11 (29–68)

47±9 (30–65)

42±12 (25–61)

45±13 (25–62)

0.540

One-way ANOVA

Gender

9 Male/6 female

9 Male/6 female

9 Male/6 female

9 Male/6 female

—

—

PMI (h)

23.7±9.9 (8–42)

27.5±10.7 (7–47)

32.5±16.1 (13–62)

33.7±14.6 (12–61)

0.147

One-way ANOVA

Brain (pH)

6.3±0.2 (5.8–6.6)

6.2±0.2 (5.8–6.5)

6.2±0.2 (5.8–6.5)

6.2±0.3 (5.8–6.6)

0.611

One-way ANOVA

Side of brain

7 Right/8 left

6 Right/9 left

8 Right/7 left

6 Right/9 left

0.864

χ2 test

Brain weight (g)

1501±164 (1305–1840)

1462±142 (1240–1740)

1441±172 (1130–1690)

1471±108 (1270–1640)

0.739

One-way ANOVA

Refrigeration interval (h)

3.6±1.4 (1–6)

7.9±5.5 (3–21)

9.5±10 (2–39)

8.5±7.2 (3–27)

0.114

One-way ANOVA

Storage days

2257±234 (1950–2693)

2353±290 (2005–2850)

2540±172 (2143–2755)

2540±233 (1987–2857)

0.003

One-way ANOVA

Age at onset (years)

—

33.9±13.3 (11–54)

21.5±8.3 (7–39)

23.2±8.0 (13–42)

0.003

One-way ANOVAa

Duration of disease (years)

—

12.7±11.1 (1–42)

20.1±9.7 (6–43)

21.3±11.4 (5–45)

0.068

One-way ANOVAa

Death by suicide

15 No

8 No/7 Yes

6 No/9 Yes

11 No/4 Yes

0.181

2χ testb

History of psychosis

—

15 without

11 with/4 without

15 with

0.100

Fisher’s testc

Fluphenazine equivalent (mg)

0

0

20 827±24 016 (0–60 000)

52 267±62 062 (0–200 000)

0.078

Unpaired t-testc

Obesity index (BMI, kg m−2)

 15–20

0

2

3

1

0.335

χ2 test

 21–25

6

3

2

3

  

 26–30

5

8

7

3

  

 31–35

1

1

1

4

  

 36–40

1

0

2

2

  

 41–45

2

1

0

2

  

SUBS

 Never

12

10

6

9

0.377

χ2 test

 Current

1

4

6

4

  

 Past

2

1

3

2

  

SUBSSEV

 None/little/social

14

11

7

10

0.056

χ2 test

 Moderate use (current, past)

1

0

5

2

  

 Heavy use (current, past)

0

3

3

3

  

 Unknown

0

1

0

0

  

ETOHSEV

 None/little/social

11

9

4

7

0.156

χ2 test

 Moderate use (current, past)

4

1

3

3

  

 Heavy use (current, past)

0

4

5

3

  

 Unknown

0

1

3

2

  

Smoking at the time of death

 Yes

4

5

3

5

0.534

χ2 test

 No

3

5

7

7

  

 Unknown

8

5

5

3

  
  1. Abbreviations: ANOVA, analysis of variance; BD, bipolar disorder; ETOHSEV, severity of alcohol abuse; MDD, major depressive disorder; PMI, post-mortem interval; SUBS, history of substance abuse; SUBSSEV, severity of substance abuse.
  2. Values are expressed as means±s.d. (minimum−maximum).
  3. aOne-way ANOVAs were used only among MDD, BD, and schizophrenia groups. History of SUBS: never, no history of use; current, drug and/or alcohol use at the time of death; past, a history of alcohol and/or drug use but not in the 6 months before death. Group differences in smoking at the time of death were analyzed after excluding unknown subjects.
  4. χ2 Test was used among MDD, BD and schizophrenia groups.
  5. Fisher’s exact test and an unpaired t-test were used with the BD and schizophrenia groups.
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