Table 2 Effects of uncountable confounding factors on the human brain FA composition

From: Abnormal fatty acid composition in the frontopolar cortex of patients with affective disorders

Parameter

FPC (BA 10)

ITC (BA 20)

 

Wilks’ λ

F

P-value

Wilks’ λ

F

P-value

Gender (60)

0.678

0.692

0.826

0.692

0.649

0.865

Side of Brain (60)

0.546

1.212

0.296

0.591

1.011

0.479

Death by Suicide (60)

0.572

1.091

0.399

0.570

1.101

0.391

SUBS (60)

0.531

0.528

0.212

0.502

0.582

0.975

SUBSSEV (59)

0.521

0.530

0.989

0.492

0.586

0.973

ETOHSEV (54)

0.331

0.861

0.701

0.339

0.838

0.734

Psychosis (60)

0.641

0.816

0.695

0.709

0.600

0.903

Diagnosis (60)

0.023

3.489

<0.0001*

0.094

1.662

0.01*

 Sch vs Cont (30)

0.263

0.583

0.831

0.419

0.289

0.989

 AD vs Cont (45)

0.061

12.808

<0.0001*

0.204

3.253

0.005*

 AD vs Sch (45)

0.054

14.667

<0.0001*

0.176

3.894

0.002*

 BD vs MDD (30)

0.177

0.969

0.579

0.307

0.470

0.904

  1. Abbreviations: AD, affective disorders (including BD and MDD); BD, bipolar disorder; Cont, normal control; ETOHSEV, severity of alcohol abuse; FA, fatty acid; FPC, frontopolar cortex; ITC, inferior temporal cortex; MDA, multiple discriminant analysis; MDD, major depressive disorder; Sch, schizophrenia; SUBS, history of substance abuse; SUBSSEV, severity of substance abuse.
  2. MDA was used for the analyses. P-values ≤0.05 are shown in bold.
  3. Numbers within parentheses indicate numbers of samples analyzed.
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