Table 2 Regions of group differences in the PFC
From: Lack of cortico-limbic coupling in bipolar disorder and schizophrenia during emotion regulation
Downregulation: BD > HC, k= 185, t -crit=2.79 | Upregulation: BD > HC, k= 197, t -crit=2.79 | ||||
|---|---|---|---|---|---|
Cluster 1: 186 voxels, peak at (40 42 −10), t=4.82, z=1.52, P=0.045 | Cluster 1: 170 voxels, peak at (46 14 −12), t=4.26, z=1.60, P=0.039 | ||||
Label | Voxels | Mean T | Label | Voxels | Mean T |
Brodmann area 11 | 27 | 3.38 | Brodmann area 38 | 59 | 3.35 |
Brodmann area 47 | 25 | 3.29 | Brodmann area 47 | 48 | 3.08 |
Brodmann area 22 | 2 | 2.99 | |||
Downregulation: HC > Sz, k= 269, t -crit=2.79 | |||||
Cluster 1: 506 voxels, peak at (50 26 6), t=5.45, z=1.71, P=0.001 | Cluster 2: 397 voxels, peak at (10 46 18), t=4.11, z=2.62, P=.004 | ||||
Label | Voxels | Mean T | Label | Voxels | Mean T |
Brodmann area 45 | 76 | 3.77 | Brodmann area 9 | 64 | 3.25 |
Brodmann area 47 | 22 | 3.47 | Brodmann area 32 | 11 | 2.93 |
Brodmann area 46 | 8 | 3.39 | Brodmann area 10 | 8 | 3.00 |
Cluster 2: 478 voxels, peak at (−22 30 46), t=5.20, z=2.58, P=0.002 | Cluster 3: 221 voxels, peak at (40 40 −10), t=4.05, z=2.11, P=.035 | ||||
Label | Voxels | Mean T | Label | Voxels | Mean T |
Brodmann area 8 | 122 | 3.55 | Brodmann area 47 | 19 | 3.29 |
Brodmann area 9 | 5 | 3.03 | Brodmann area 10 | 12 | 3.04 |
Brodmann area 32 | 2 | 2.94 | Brodmann area 11 | 7 | 2.96 |
Cluster 3: 970 voxels, peak at (−46 2 −24), t=4.83, z=1.56, P<0.001 | Upregulation: Sz > HC, k= 280, t -crit=2.79 | ||||
Label | Voxels | Mean T | Cluster 1: 298 voxels, peak at (40 42 −10), t=4.40, z=2.80, P=0.036 | ||
Brodmann area 21 | 162 | 3.31 | Label | Voxels | Mean T |
Brodmann area 38 | 101 | 3.26 | Brodmann area 10 | 16 | 2.98 |
Brodmann area 47 | 90 | 3.21 | Brodmann area 47 | 12 | 3.46 |
Cluster 4: 557 voxels, peak at (−12 64 22), t=4.09, z=1.35, P=0.001 | Brodmann area 11 | 7 | 3.03 | ||
Label | Voxels | Mean T | Cluster 2: 436 voxels, peak at (8 42 18), t=4.25, z=1.98, P=0.004 | ||
Brodmann area 10 | 154 | 3.10 | Label | Voxels | Mean T |
Brodmann area 11 | 5 | 2.97 | Brodmann area 32 | 44 | 3.14 |
Brodmann area 9 | 4 | 3.13 | Brodmann area 9 | 25 | 3.36 |
Downregulation: BD > Sz, k= 260, t -crit=2.81 | Brodmann area 10 | 22 | 3.28 | ||
Cluster 1: 777 voxels, peak at (50 28 6), t=5.89, z=2.25, P<0.001 | |||||
Label | Voxels | Mean T | |||
Brodmann area 45 | 64 | 3.83 | |||
Brodmann area 47 | 57 | 3.63 | |||
Brodmann area 46 | 15 | 3.10 | |||
Cluster 2: 317 voxels, peak at (26 24 −20), t=4.22, z=1.53, P=0.023 | |||||
Label | Voxels | Mean T | |||
Brodmann area 38 | 82 | 3.19 | |||
Brodmann area 47 | 37 | 3.35 | |||
Brodmann area 11 | 16 | 3.42 | |||
