Table 1 Sample characteristics for the white subset and by treatment site
From: Neurotrophic gene polymorphisms and response to psychological therapy
White sample ( N= 374) | Sydney subset ( N= 262) | Reading subset ( N= 112) | t/χ 2 | d.f. | P | |
---|---|---|---|---|---|---|
Pre-treatment | ||||||
Child agea | 6–13; 9.46 (1.82) | 6–13; 9.45 (1.92) | 6–12; 9.47 (1.59) | 0.10 | 251e | 0.927 |
Child gender (m:f) | 188:185d | 134:127 | 54:58 | 0.31 | 1 | 0.580 |
NGF genotype frequencies (CC; CT; TT)b | 29.5; 47.8; 22.7 | 28.8; 48.1; 23.1 | 31.1; 47.2; 21.7 | 0.21 | 2 | 0.901 |
BDNF genotype frequencies (GG; GA; AA)b | 67.5; 29.5; 3.0 | 69.3; 27.2; 3.4 | 63.0; 35.2; 1.9 | 2.76 | 2 | 0.251 |
Primary disorder severitya | 4–8; 6.16 (0.95) | 4–8; 6.43 (0.83) | 4–8; 5.53 (0.91) | −9.36 | 372 | 0.000 |
Post-treatment | ||||||
Primary disorder severitya | 0–8; 3.15 (2.09) | 0–8; 3.43 (1.85) | 0–8; 2.39 (2.48) | −3.66 | 131e | 0.000 |
Primary anxiety responders (N=336)c | 174 (51.8) | 125 (51.2) | 49 (53.3) | 0.11 | 1 | 0.740 |
All anxiety responders (N=336)c | 126 (37.3) | 93 (38.1) | 33 (35.1) | 0.26 | 1 | 0.608 |
Follow-up | ||||||
Primary disorder severitya | 0–8; 2.73 (2.06) | 0–7; 3.05 (1.87) | 0–8; 1.58 (2.30) | −4.52 | 80e | 0.000 |
Primary anxiety responders (N=278)c | 175 (62.9) | 135 (61.6) | 40 (67.8) | 0.75 | 1 | 0.385 |
All anxiety responders (N=278)c | 128 (46.0) | 99 (45.2) | 29 (49.2) | 0.29 | 1 | 0.589 |