Table 2 Genotypic frequencies and logistic regression analyses for NGF rs6330 and BDNF rs6265 by treatment response (additive model coded as: −1, 0, 1)
From: Neurotrophic gene polymorphisms and response to psychological therapy
Time | Model | A1/A1 | A1/A2 | A2/A2 | Additive | |
|---|---|---|---|---|---|---|
N (%) | N (%) | N (%) | OR (95% CI) | P | ||
NGF rs6330 | ||||||
Post-treatment | Primary anxiety responders | 46 (47.9) | 87 (54.7) | 40 (53.3) | 0.88 (0.66–1.20) | 0.443 |
All anxiety responders | 34 (35.1) | 63 (39.6) | 28 (37.3) | 0.94 (0.69–1.28) | 0.714 | |
Follow-up | Primary anxiety responders | 42 (53.2) | 87 (63.5) | 46 (76.7) | 0.60 (0.42–0.85) | 0.005 |
All anxiety responders | 32 (40.5) | 62 (45.3) | 34 (56.7) | 0.73 (0.52–1.02) | 0.067 | |
BDNF rs6265 | ||||||
Post-treatment | Primary anxiety responders | 113 (50.2) | 54 (54.5) | 4 (44.4) | 0.92 (0.61–1.38) | 0.694 |
All anxiety responders | 87 (38.5) | 33 (33.0) | 3 (33.3) | 1.22 (0.79–1.88) | 0.361 | |
Follow-up | Primary anxiety responders | 122 (64.2) | 48 (61.5) | 3 (42.9) | 1.24 (0.78–1.98) | 0.358 |
All anxiety responders | 85 (44.7) | 38 (48.7) | 3 (42.9) | 0.91 (0.58–1.43) | 0.670 | |
