Table 1 Demographics and clinical characteristicsa

From: TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders

 

Schizophrenia ( n= 300)

Bipolar disorder ( n= 223)

Other psychoses ( n= 73)

Healthy controls ( n= 385)

Demographics

 Age, yearsb

32.6 (9.7)

36.0 (12.1)

33.0 (10.3)

34.6 (10.0)

 Sex, n (% male)

161 (53.7)

85 (38.1)

47 (64.4)

197 (51.2)

 Age at onset, yearsc

27.2 (8.6)

28.3 (11.1)

26.1 (14.6)

—

Symptom ratings

 PANSS total score

64.2 (16.9)

46.3 (10.7)

55.8 (14.8)

—

 GAF symptom

41.3 (11.3)

57.0 (11.7)

48.5 (13.6)

—

 GAF function

42.5 (10.3)

54.6 (12.2)

50.4 (14.1)

—

Medication

N (%)

N (%)

N (%)

 

 Antipsychotic

268 (89.3)

113 (50.6)

54 (74.0)

—

 Lithium

7 (2.3)

34 (15.2)

0 (0)

—

 Anticonvulsiva

60 (20.0)

98 (44.0)

8 (11.0)

—

 Antidepressants

89 (29.7)

84 (37.6)

26 (35.6)

—

 Sedatives

28 (12.4)

34 (11.3)

16 (21.9)

—

  1. Abbreviations: GAF, Global Assessment of Functioning; PANSS, Positive and Negative Syndrome Scale.
  2. aMean and standard deviation are reported unless otherwise specified.
  3. bAge was defined as age at phenotype assessments.
  4. cAge at onset was defined as age at first contact with the mental health service owing to a primary symptom.
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