Table 3 Schizophrenia candidate genes (from the SZgene database) with expression levels significantly associated with cis eSNPs in brain tissue

Symbol	Chr.	Position ^a	*Study_ID*	*Brain_Region*	*SNP*	*S_Position*	P *-value* ^b	*Adjusted* P *-value*
HTR2A	13	(R): 47407513-47470175	Study01	Frontal cortex	rs1923882	47411661	3.08E−10	9.45E−05
HTR2A	13	(R): 47407513-47470175	Study07	Frontal cortex	rs1923882	47411661	2.54E−08	7.80E−03
PLXNA2	1	(R): 208195587-208417665	Study01	Frontal cortex	rs6659522	208199100	3.26E−10	1.00E−04
PLXNA2	1	(R): 208195587-208417665	Study03	Frontal cortex	rs6659522	208199100	1.03E−09	3.15E−04
PLXNA2	1	(R): 208195587-208417665	Study07	Frontal cortex	rs6702082	208206946	4.04E−08	1.24E−02
SRR	17	(F): 2207248-2228553	Study01	Frontal cortex	rs16952025	2116798	3.24E−08	9.94E−03
SRR	17	(F): 2207248-2228553	Study03	Frontal cortex	rs16952025	2116798	8.86E−08	2.72E−02
SRR	17	(F): 2207248-2228553	Study07	Frontal cortex	rs16952025	2116798	1.65E−13	5.06E−08
SRR	17	(F): 2207248-2228553	Study17	Hippocampus	rs16952025	2116798	9.60E−11	2.95E−05
TCF4	18	(R): 52889562-53255860	Study01	Frontal cortex	rs1261085	52889967	1.08E−08	3.33E−03
TCF4	18	(R): 52889562-53255860	Study03	Frontal cortex	rs1261134	52931763	1.98E−15	6.09E−10
TCF4	18	(R): 52889562-53255860	Study05	Frontal cortex	rs1261073	52907820	2.18E−12	6.68E−07
TCF4	18	(R): 52889562-53255860	Study07	Frontal cortex	rs1261073	52907820	1.57E−15	4.82E−10
TCF4	18	(R): 52889562-53255860	Study16	Thalamus	rs1261134	52931763	3.86E−08	1.18E−02

Abbreviation: eSNP, expressed single-nucleotide polymorphism.
Genome build;hg19.
^aF and R represent the forward orientation or reverse orientation on a chromosome.
^bAdjusted P-value using Bonferroni method.

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