Table 2 Combined effect sizes for the associations between positive or negative environmental factors and child outcomes for the various 5HTTLPR genotypes in the total set of studies (k=77)
Genotype | Positive environment | Negative environment | Contrast | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
K | N | r | 95% CI | Q | k | N | r | 95% CI | Q | Q | P | |
(1) ss | 7 | 312 | 0.17** | 0.07∼0.25 | 5.12 | 10 | 715 | 0.31** | 0.24∼0.37 | 6.51 | 6.17 | .01 |
(2) ss/sl | 9 | 1004 | 0.27** | 0.09∼0.43 | 110.81** | 6 | 1312 | 0.09 | −0.13∼0.30 | 20.16** | 1.59 | .21 |
(3) sl | 4 | 568 | 0.17* | 0.01∼0.33 | 9.36* | 9 | 1772 | 0.20** | 0.08∼0.31 | 30.71** | 0.07 | .80 |
(4) sl/ll | 3 | 415 | 0.06* | 0.01∼0.11 | 0.33 | 1 | 170 | 0.00 | −0.15∼0.15 | n.a. | n.a. | n.a. |
(5) ll | 13 | 1199 | 0.11** | 0.04∼0.19 | 24.80* | 15 | 1894 | 0.06 | −0.01∼0.12 | 12.34 | 1.30 | .26 |
(6) all ss/sl (1+2+3) | 20 | 1884 | 0.21** | 0.12∼0.30 | 135.48** | 25 | 3739 | 0.22** | 0.14∼0.31 | 79.86** | 0.03 | .86 |
