Table 1 Estimated means and 95% confidence intervals (CI) from the multilevel model of methylation (%5MeC) averaged across CpG units of each target sequence and descriptive values of blood cell count for each sampling time (pre-stress, post-stress and follow-up)

From: Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF ) after acute psychosocial stress

Sampling time

 

Pre-stress

Post-stress

Follow-up

 

M

95% CI

M

95% CI

M

95% CI

Methylation (%5MeC)

      

 OXTR 1

17.64

16.48−18.81

18.02

16.85−19.19

16.98

15.79−18.16

 OXTR2 a

5

4.67−5.35

5.06

4.73−5.42

4.76

4.42−5.11

 BDNF a

6.61

6.10−7.15

6.56

6.05−7.10

6.31

5.80−6.84

Blood cell count

      

 Leukocytesb

6.53

6.25−6.80

7.01

6.69−7.32

6.74

6.41−7.06

 Lymphocytesc

30.59

28.98−32.21

32.61

30.85−34.36

26.74

25.09−28.40

 Monocytesc

8

7.57−8.43

8.24

7.75−8.74

7.54

7.06−8.01

 Granulocytesc

62.12

60.63−63.60

59.60

58.05−61.16

65.45

63.55−67.34

  1. Abbreviations: BDNF, brain-derived neurotrophic factor; 95% CI, 95% confidence interval; M, mean; OXTR, oxytocin receptor.
  2. aEstimates were re-transformed from natural logarithm to %5MeC;
  3. bNumber × 103/μl;
  4. c% of leukocytes.
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