Table 1 Demographic, lifestyle and clinical characteristics of older men included in this study, as well as those with depression, tHcy⩾15 μmol l−1 or who were using aspirin and B-vitamins
From: Aspirin decreases the risk of depression in older men with high plasma homocysteine
Study population N=3687 | Depression N=513 | tHcy⩾15 μmol l N=934 | Aspirin use N=1511 | B-vitamin use N=154 | |||||
|---|---|---|---|---|---|---|---|---|---|
n (%) | n (%) | P-value | n (%) | P-value | n (%) | P-value | n (%) | P-value | |
tHcy⩾15 μmol l | 934 (25.3) | 161 (31.4) | 0.001 | — | — | 387 (25.6) | 0.745 | 24 (15.6) | 0.004 |
Aspirin use | 1511 (41.0) | 213 (41.5) | 0.789 | 387 (41.4) | 0.745 | — | — | 73 (47.4) | 0.098 |
B-vitamin use | 154 (4.2) | 35 (6.8) | 0.001 | 24 (2.6) | 0.004 | 73 (4.8) | 0.098 | — | — |
Age in years | 0.061 | <0.001 | 0.001 | 0.380 | |||||
69–74 | 1849 (50.1) | 230 (44.8) | 356 (38.1) | 709 (46.9) | 67 (43.5) | ||||
75–79 | 1218 (33.0) | 183 (35.7) | 353 (37.8) | 512 (33.9) | 58 (37.7) | ||||
80–84 | 531 (14.4) | 87 (17.0) | 181 (19.4) | 256 (16.9) | 24 (15.6) | ||||
85+ | 89 (2.4) | 13 (2.5) | 44 (4.7) | 34 (2.2) | 5 (3.2) | ||||
Australian migrant | 1379 (37.4) | 181 (35.3) | 0.280 | 488 (43.7) | <0.001 | 527 (34.9) | 0.009 | 69 (45.1) | 0.045 |
Education:⩾high school | 1861 (50.5) | 268 (52.2) | 0.399 | 460 (49.3) | 0.391 | 772 (51.2) | 0.515 | 87 (56.9) | 0.109 |
Living alone | 597 (16.2) | 100 (19.5) | 0.029 | 186 (19.9) | <0.001 | 247 (16.3) | 0.832 | 31 (20.1) | 0.175 |
Smoking | <0.001 | <0.001 | 0.054 | 0.557 | |||||
Never | 1243 (33.7) | 136 (26.5) | 258 (27.7) | 504 (33.4) | 52 (33.8) | ||||
Past | 2254 (61.2) | 340 (66.3) | 623 (66.8) | 944 (62.5) | 97 (63.0) | ||||
Current | 188 (5.1) | 37 (7.2) | 51 (5.5) | 62 (4.1) | 5 (3.2) | ||||
Charlson index⩾3 | 473 (12.8) | 105 (20.5) | <0.001 | 189 (20.2) | <0.001 | 247 (16.3) | <0.001 | 36 (23.4) | <0.001 |
Antidepressant use | 220 (6.0) | 153 (29.8) | <0.001 | 69 (7.4) | 0.034 | 112 (7.4) | 0.002 | 12 (7.8) | 0.329 |
