Table 2 Associations between the factor dimension ‘negative mood delusions’ and rs9875793 and the seven SLC2A2 SNPs in the German GWAS sample (see Figure 2)

From: Genome-wide significant association between a ‘negative mood delusions’ dimension in bipolar disorder and genetic variation on chromosome 3q26.1

SNP data

 

Association data

    

German sample

    

Allelic χ2 model

MAF

Marker

Chromosome

Alleles

Factor dimension

PG

OR

High scores

Low scores

rs9875793

3

A/G

Negative mood delusions

4.65 × 10−8

2.66

0.27

0.12

rs10513684

3

T/C

Negative mood delusions

NS

1.06

0.04

0.04

rs10513685

3

A/G

Negative mood delusions

NS

0.71

0.10

0.14

rs1499821

3

A/G

Negative mood delusions

5.80 × 10−8

2.65

0.27

0.12

rs8192675

3

G/A

Negative mood delusions

0.0017

1.68

0.37

0.26

rs5400

3

T/C

Negative mood delusions

NS

0.71

0.10

0.14

rs11924032

3

A/G

Negative mood delusions

0.00017

1.87

0.34

0.22

  1. Abbreviations: MAF, minor allele frequency; NS, non significant; OR, odds ratio referring to minor allele; SNPs, single-nucleotide polymorphisms.
  2. Alleles, minor/major allele. Minor allele refers to dbSNP build129, and was determined in each analysis in patients with and patients without the trait.
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