Figure 1 | Translational Psychiatry

Figure 1

From: Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

Figure 1

Venn diagram showing the overlap of three gene complexes and their relative genetic overlap within the proteins of the full human postsynaptic density (hPSD). Numbers of genes in each gene set and overlap of these are also shown. Note: The full hPSD consists of all genes associated with proteins in the hPSD.18 The genetic constituents of the AMPA-RC (α-amino-3-hydroxy-5-methyl-4-isoxazoiepropionic acid receptor complex), mGlu5-RC (metabotropic glutamate 5 receptor complex) and NMDA-RC (N-methyl-D-aspartate receptor complex) are taken from mouse-based proteomic experiments.19

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