Table 2 The rs1133503 genotype distribution for European American and African American subjects with panic disorder, major depressive disorder, post-traumatic stress disorder and antisocial personality disorder
From: The α-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder
Group | Genotype count (frequency) | P-valuea | ||
|---|---|---|---|---|
TT | CT | CC | ||
European American | ||||
Non-PD | 694 (36.9%) | 867 (46.1%) | 321 (17.1%) | |
PD | 49 (25.7%) | 107 (56.0%) | 35 (18.3%) | 0.007 |
Non-MDD | 619 (36.1%) | 800 (46.7%) | 296 (17.3%) | |
MDD | 109 (34.9%) | 150 (48.1%) | 53 (17.0%) | 0.96 |
Non-PTSD | 636 (35.4%) | 858 (47.8%) | 301 (16.8%) | |
PTSD | 108 (38.4%) | 119 (42.4%) | 54 (19.2%) | 0.1 |
Non-ASPD | 643 (35.8%) | 837 (46.6%) | 316 (17.6%) | |
ASPD | 91 (35.7%) | 126 (49.4%) | 38 (14.9%) | 0.68 |
African American | ||||
Non-PD | 1007 (42.0%) | 1036 (43.2%) | 355 (14.8%) | |
PD | 28 (45.9%) | 27 (44.3%) | 6 (9.84%) | 0.49 |
Non-MDD | 924 (42.9%) | 923 (42.8%) | 308 (14.3%) | |
MDD | 106 (38.3%) | 125 (45.1%) | 46 (16.6%) | 0.278 |
Non-PTSD | 910 (42.7%) | 918 (43.1%) | 302 (14.2%) | |
PTSD | 128 (39.0%) | 142 (43.3%) | 58 (17.7%) | 0.18 |
Non-ASPD | 913 (42.4%) | 924 (42.9%) | 319 (14.8%) | |
ASPD | 116 (40.7%) | 128 (44.9%) | 41 (14.4%) | 0.84 |
