Table 3 MANEA rs1133503 genotype is associated with panic disorder and generalized social anxiety disorder diagnosis in different European American samples
From: The α-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder
Group | Genotype count (frequency) | Odds ratio (95% CI) a | P-value | |||
---|---|---|---|---|---|---|
TT | CT | CC | ||||
Sample 1 - panic disorder | Cases | 49 (25.7%) | 107 (56.0%) | 35 (18.3%) | ||
Controls | 694 (36.9%) | 867 (46.1%) | 321 (17.1%) | 1.7 (1.21–2.40)b | 0.002 | |
Sample 2 - panic disorder | Cases | 36 (25.4%) | 74 (52.1%) | 32 (22.5%) | ||
Controls | 188 (34.2%) | 268 (48.7%) | 94 (17.1%) | 1.53 (1.01–2.33)c | 0.043 | |
Sample 3 - GSAD | Cases | 28 (21.4%) | 87 (66.4%) | 16 (12.2%) | ||
Controls | 74 (36.6%) | 96 (47.5%) | 32 (15.8%) | 2.15 (1.27–3.64)d | 0.004 |