Figure 2 | Translational Psychiatry

Figure 2

From: Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

Figure 2

MeCP2 mRNA and protein expression in CON vs ASD. (a) MeCP2 mRNA expression is increased in ASD vs CON (*P=0.01). Values were corrected for expression of housekeeping gene GAPDH mRNA. All values are expressed as means±s.e.m. (b) MeCP2 protein levels fail to increase in ASD samples relative to CON (P=0.45, n=10). MeCP2 protein levels in ASD were expressed as percentage relative to CON (100%). (c) Representative immunoblots show a major band of 75 kDa for MeCP2 and 42 kDa for β-actin. ASD, autism spectrum disorder; CON, control.

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