Figure 1

Immune repertoire of RAG-1^−/−, RAG-1^−/−/OT-I and RAG-1^−/−/OT-II mice. Thymocytes and lymphocytes from male wild-type (WT), RAG-1^−/−, RAG-1^−/−/OT-I and RAG-1^−/−/OT-II mice were analyzed for CD4 and CD8 expression. The dot plots show the T-cell profiles of RAG-1^−/−, RAG-1^−/−/OT-I and RAG-1^−/−/OT-II mice in the thymus (upper panel) and in the periphery (lower panel) compared with WT C57BL/6 control mice. The percentage of the cells in each quadrant is given.