Figure 3

CD4⁺ but not CD8⁺ T cells revert the increased digging and marble-burying behavior of RAG-1^−/− mice. The bar graphs show the total number of digging bouts, buried marbles and the latency to dig (expressed in seconds) in RAG-1^−/−/OT-I (a) or RAG-1^−/−/OT-II (b) compared with RAG-1^−/− during the 15-min marble-burying test. Values are expressed as mean±s.e.m. of six mice and are representative of n=3–4 separate experiments. **P<0.01 indicates significant values compared with RAG-1^−/− mice (Mann–Whitney U-test).