Figure 6 | Translational Psychiatry

Figure 6

From: CD4+ but not CD8+ T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice

Figure 6

Depletion of CD4 or CD8 T cells does not induce anxiety-like behavior in C57/BL6 mice. C57/BL6 mice received an intraperitoneal injection of anti-CD4 (250 μg), anti-CD8- (250 μg) depleting antibodies or IgG control, and then tested in the digging and marble-burying test. The bar graphs show the total number of digging bouts, buried marbles and the latency to dig (expressed in seconds) in mice treated as indicated and assessed before the treatment (day 0) or after 2, 5 and 7 days (day 2, day 5 and day 7, respectively). Values are expressed as mean±s.e.m. of 6–8 mice.

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