Figure 7
Repopulation of RAG1−/− mice with CD4 or CD8 T cells does not affect their anxiety-like behavior. RAG1−/− mice received an intraperitoneal injection of purified CD4 (2 × 106) or CD8 (2 × 106) T cells and then tested in the digging and marble-burying test. The bar graphs show the total number of digging bouts, buried marbles and the latency to dig (expressed in seconds) in mice assessed before the cell transfer (day 0) or after 4 and 7 days (day 4 and day 7, respectively). Values are expressed as mean±s.e.m. of 6–8 mice.
