Figure 8

CD4⁺ but not CD8⁺ T cells revert the impaired nest construction of RAG-1^−/− mice. (a) Representative pictures of the nestlet shredding activity of wild-type (WT), RAG-1^−/−, RAG-1^−/−/OT-I and RAG-1^−/−/OT-II during an overnight test. (b) Quantitative analysis of nestlet shredding activity expressed as grams of nestlet shredded after an overnight test. Values are expressed as mean±s.e.m. of six mice and are representative of n=3–4 separate experiments. ^§P<0.05 and **P<0.01 indicate significant values compared with WT C57BL/6 control and RAG^−/− mice, respectively (Mann–Whitney U-test).