Table 1 Demographic information for the four diagnostic groups

From: Expression of GABAA α2-, β1- and ɛ-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder

 

Bipolar

Depression

Control

Schizophrenia

F or χ2-test

P-value

Age

42.33 (11.72)

46.53 (9.31)

48.07 (10.66)

44.53 (13.11)

0.73

0.54

Sex

6 F, 9 M

6 F, 9 M

6 F, 9 M

6 F, 9 M

0

1.0

Race

14 W, 1 B

15 W

14 W, 1 B

12 W, 3 A

14.7

0.10

PMI

32.53 (16.12)

27.47 (10.73)

23.73 (9.95)

33.67 (14.62)

1.85

0.15

pH

6.18 (0.23)

6.18 (0.22)

6.27 (0.24)

6.16 (0.26)

0.60

0.62

Side of brain

7 L, 8 R

9 L, 6 R

7 L, 8 R

9 L, 6 R

0.85

0.84

Brain weight

1441.2 (171.5)

1462 (142.1)

1501 (164.1)

1471.7 (108.2)

0.42

0.74

Family history

0.93 (0.8)

0.73 (0.46)

0.13 (0.52)

1.13 (0.83)

29.84

0.0001

Suicidal death

9 (5 Violent)

9 (4 Violent)

0

6 (2 Violent)

15.9

0.014

Drug/alcohol history

0.8 (0.77)

0.4 (0.63)

0.33 (0.72)

0.53 (0.74)

6.42

0.38

Age of onset

21.47 (8.35)

33.93 (13.29)

—

23.2 (7.96)

3.61

0.001

Duration

20.13 (9.67)

12.67 (11.06)

—

21.67 (11.24)

0.034

0.86

Severity of substance abuse

1.93 (1.98)

1.07 (1.98)

0.13 (0.52)

1.20 (1.86)

2.82

0.046

Severity of alcohol abuse

2.27 (1.98)

1.8 (2.01)

1.07 (1.03)

1.47 (1.59)

1.34

0.27

Fluphenazine (lifetime)

20,826.67 (24,015.96)

—

—

52,266.67 (62,061.57)

3.35

0.078

Alcohol dependence

13.3%

13.3%

0%

0%

4.29

0.23

Alcohol abuse

6.7%

6.7%

0%

0%

1.05

0.79

Substance dependence

6.7%

0%

0%

6.7%

2.07

0.56

Substance abuse

20.0%

6.7%

0%

6.7%

4.15

0.25

Antidepressant use

53.3%

60.0%

0%

33.3%

14.1

0.003

  1. Abbreviations: A, Asian; B, Black; F, female; L, left; M, male; PMI, postmortem interval; R, right; W, Whites.
  2. Rating scale for drug/alcohol history: 0, never; 1, current; 2, past. Rating scale for severity of substance abuse: 0, little/none; 1, social; 2, moderate use/past; 3, moderate use/present; 4, heavy use/past; 5, heavy use/present. Rating scale for severity of alcohol abuse: 0, little/none; 1, social (one to two drinks per day); 2, moderate use/past; 3, moderate use/present; 4, heavy use/past; 5, heavy use/present.
Back to article page