Table 4 mRNA expression for 12 GABAA receptor subunits in the lateral cerebella of subjects with schizophrenia and mood disorders

From: Expression of GABAA α2-, β1- and ɛ-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder

  

Schizophrenia

Bipolar disorder

Major depression

 

ANOVA

Fold change

P-value

Fold change

P-value

Fold change

P-value

GABRA1

0.012

0.713

0.011

0.949

0.707

0.618

0.009

GABRA2

0.126

0.563

0.017

0.688

0.111

0.688

0.099

GABRA3

0.505

0.531

0.139

0.589

0.289

0.865

0.599

GABRA5

0.118

0.754

0.127

1.094

0.621

0.735

0.206

GABRA6

0.385

0.994

0.967

0.674

0.210

0.789

0.217

GABRB1

0.684

0.997

0.989

0.781

0.319

0.937

0.743

GABRB2

0.866

1.113

0.644

0.915

0.784

1.128

0.583

GABRB3

0.232

1.473

0.044

1.317

0.115

1.375

0.071

GABRD

0.233

0.678

0.051

0.602

0.101

0.887

0.632

GABRE

0.400

1.046

0.859

1.320

0.196

0.905

0.639

GABRG2

0.238

1.118

0.419

0.758

0.168

0.888

0.461

GABRG3

0.188

0.785

0.373

0.877

0.625

0.450

0.081

  1. Abbreviations: ANOVA, analysis of variance; C, control; GABAA, γ-aminobutyric acid (A); S, schizophrenia; B, bipolar disorder; D, major depression.
  2. Note: ANOVA based on six comparisons: C versus S, C versus B, C versus D, S versus B, S versus D and B versus D.
  3. Bold entries represent significant fold changes and P values.
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