Figure 1
From: A rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation

Burden of novel unique variants in the Wnt pathway in autism spectrum disorders (ASD). Percentage of individuals carrying a novel unique variant that was nonsynonymous and predicted to be deleterious by the PolyPhen-2 algorithm, compared with nonsynonymous, synonymous, untranslated region (UTR) or intronic single-nucleotide polymorphisms (SNPs). *P<0.05; NS, not significant.