Table 3 Detailed description of psychiatric history and manifestations of CTX patients drawn from the medical literature
From: Psychiatric manifestations in cerebrotendinous xanthomatosis
Psychiatric symptoms and signs (age) |
|---|
P1: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, (<10) |
P2: (MOOD/AFFECTIVE disorder) Depressive episode, suicidal ideation and threats, aggressivity, assault threats, disinhibition, poor impulse control, fecal incontinence (49) |
P3: NS (32) |
P4: (BEHAVIORAL/PERSONALITY disorder) Apathy, spasmodic laughter/cry (43) |
P5: (BEHAVIORAL/PERSONALITY disorder) Behavioral alteration, logorrhea, psychomotor excitation, distractibility, fleeting ideas, emotional lability, no spasmodic laughter/cry (39) |
P6: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder (childhood), psychiatric institution (23) |
P7: (MOOD/AFFECTIVE disorder) Mood instability, affective disorder, predominantly depressive periods, phases of agitation/excitation even aggressivity (49) |
P8: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, irritability, agitation (6 psychiatric hospitalizations before 32) personality disturbance, hypersexuality?(32) paranoid id., suicidal (41) |
P9: (PSYCHOSIS) Psychosis atypical, paranoid delusion (37) |
P10: (CATATONIA) Catatonia reactive to family stress?, akinetic, mute, fixed postures, urinary–fecal incontinence (27) |
P11: (BEHAVIORAL/PERSONALITY disorder) Aggressivity, agitated, required many hospitalizations (22) |
P12: NS (25) |
P13: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, aggressivity, destructive behavior (24) |
P14: NS (between 17–33) |
P15: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder (early childhood) |
P16: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, lack of affection and neglect towards family, restlessness, disinhibition, apathy, abulia, PREDEMENTIA (38–40) |
P17: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, behavioral changes |
P18: (PSYCHOSIS) Psychosis |
P19: (MOOD/AFFECTIVE disorder) Depression |
P20: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, Behavioral changes |
P21: (PSYCHOSIS) Psychosis |
P22: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, Behavioral changes |
P23: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, Behavioral changes |
P24: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, Behavioral changes |
P25: (MOOD/AFFECTIVE disorder) Depression |
P26: (PSYCHOSIS) Psychosis |
P27: (PSYCHOSIS) Psychosis |
P28: (MOOD/AFFECTIVE disorder) Depression, irritability, insomnia, crying spells, poor appetite, agitated; bullied constantly by her siblings with CTX since early teens (29) |
P29: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, aggressivity towards sister (adolescence) |
P30: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, Aggressivity towards sister (adolescence) |
P31: (MOOD/AFFECTIVE disorder) Depression (>26, 26–37) |
P32: (MOOD/AFFECTIVE disorder) Depression severe (49) |
P33: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, poor judgment, self-neglect, altered sexual behavior, dysexec, irritability, anxiety (44) PERSONALITY disturbance profound, breakdown in social behavior (53) |
P34: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, spasmodic laughter |
P35: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, BEHAVIORAl disorder, aggressivity, irritability, awake at nights, anxiety, fight and hitting and hitting people (10) |
P36: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, odd behavior could lose his job, but no aggressivity (>18) |
P37: NS (40s) |
P38: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disturbance at military, introverted (adolescence), paranoid delusions, undifferentiated schizophrenia and schizoid personality disturbance (20–40) |
P39: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, ADHD (late childhood, adolescence) |
P40: (MOOD/AFFECTIVE disorder) Depression, benzodiazepine abuse, suicidal ideation |
P41: (MOOD/AFFECTIVE disorder) Mood/affective, bipolar disorder, schizophrenia |
P42: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, aggressivity, irritability |
P43: (BEHAVIORAL/PERSONALITY disorder) Behavioral/personality disorder, aggressivity, irritability |
P44: (MOOD/AFFECTIVE disorder) Anxiety |
P45: (MOOD/AFFECTIVE disorder) Dysthymia |
P46: NS |
P47: NS |
P48: NS |
P49: NS |
P50: NS |
P51: NS |
P52: NS |
P53: NS |
P54: NS |
