Table 2 Enriched in neurons

From: Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients

 

BP neurons

Control neurons

GO term

n

P*⩽

n

P*⩽

Synapse

183

2.1 × 10−22

180

1.5 × 10−21

Neuron projection

173

3.4 × 10−20

176

1.2 × 10−21

Neuron development

161

4.5 × 10−12

167

7.2 × 10−15

Voltage-gated cation channel activity

66

7.8 × 10−4

61

1.6 × 10−2

  1. Abbreviation:
  2. BP, bipolar disorder;
  3. GO, Gene Ontology; *, Bonferroni correction.
  4. Neurons differentiated from BP and control iPSC expressed similar sets of transcripts, many associated with neuronal differentiation, synapses and channel activity.
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