Table 1 Demographic, clinical and neuropsychological data of study participants

From: Hippocampal structural and functional changes associated with electroconvulsive therapy response

Demographics

ECT mean (s.d.) or ratio

HC mean (s.d.) or ratio

P-value

 

Age (MDD=19; HC=20)

65.3 (8.0)

64.9 (9.4)

0.87

 

Gender (M/F)

6/13

8/12

0.58

 
 

Pre-ECT mean (s.d.)

Post-ECT mean (s.d.)

P-value

Cohen’s d

HDRS-24

 Responders (n=15)

33.7 (8.8)

4.7 (4.6)

<0.01

4.11

 Non-responders (n=4)

28.5 (6.4)

22.0 (5.1)

0.22

1.13

HES

 Responders

11.8 (3.6)

1.9 (2.3)

<0.01

3.30

 Non-responders

10.0 (1.6)

7.3 (3.8)

0.22

0.95

RBANS

 Total scale

84.8 (23.6)

83.0 (8.0)

0.75

0.07

 Visualspatial/monstruction

94.7 (25.6)

89.7 (35.0)

0.39

0.16

 Language

95.5 (11.6)

95.7 (20.0)

0.96

−0.01

 Attention

85.1 (22.4)

79.9 (29.3)

0.38

0.20

 Delayed memory

86.7 (21.3)

84.1 (29.7)

0.69

0.10

 Immediate memory

76.3 (23.0)

85.5 (23.6)

0.04

−0.39

Percent retained

0.41 (0.27)

0.660 (0.34)

0.04

−0.62

Trails (in s)

 A

51.6 (27.5)

45.9 (14.1)

0.32

0.26

 B

155.7 (79.4)

139.1 (74.7)

0.48

0.22

  1. Abbreviations: ECT, electroconvulsive therapy; F, female; HC, healthy comparison; HDRS, Hamilton Depression Rating Scale; M, male; MDD, major depressive disorder; RBANS, Repeatable Assessment for Neuropsychological Status.