Figure 1 | Translational Psychiatry

Figure 1

From: Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates

Figure 1

Obesity and depression-like phenotypes in db/db mice. (a) Body weight. (b) Food intake. n=9–10 per group, ***P<0.001 compared with wild-type mice. (c) Plasma leptin levels. (d) Plasma insulin levels. n=5 per group, ***P<0.001 compared with wild-type mice. (e) Sucrose preference test. Left panel, sucrose intake; right panel, sucrose preference. n=9–10 per group, *P<0.05 compared with wild-type mice. (f) Saccharin preference test. Left panel, saccharin intake; right panel, saccharin preference. n=9 per group, **P<0.01 compared with wild-type mice. (g) Forced swim test. n=8–9 per group, *P<0.05 compared with wild-type mice.

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