Figure 1

Temporal discounting and dopamine function in the ventral striatum. Spearman nonparametric correlations between temporal discounting rate (k) and dopamine release (Vstr dBP_ND; positive values indicate dopamine release) in pathological gamblers (a) and controls (b). Correlations between the baseline ventral striatum D2/D3 availability (Vstr BP_ND) and k in pathological gamblers (c) and controls (d). Solid circles represent PG subjects. Open circles represent healthy volunteers. BP_ND, non-displaceable binding potential; Vstr, ventral striatum; PG, pathological gambling.