Figure 3
Higher dorsal striatal dopamine synthesis capacity associated with higher temporal discounting in Parkinson patients. (a) The correlation between the left caudate FDOPA uptake (Kiref) and temporal discounting rate (k). Solid circles represent patients with BAs. Open circles represent patients without BAs. (b) The pseudo-T values (red–yellow scale) for positive correlations between FDOPA Kiref and temporal discounting rate k (peak at 22 30 −23, cluster size k=494, PFWE=0.003). The image is thresholded to show only clusters with PFWE<0.05. The background image is the average normalized T1-weighted MRI of the subjects in Study 2. The images are displayed in radiological convention (that is, the right side of the image corresponds to the left side of the patient). BA, behavioral addiction; FDOPA, fluorodopa; FWE, family-wise error.
