Figure 3

Effect of haloperidol treatment on the striatal PDE10A protein levels assessed by western blotting. (a) Two-colour western blot with striatal lysate from the six haloperidol (H)- and six vehicle (V)-treated rats loaded in alternate wells. PDE10A (green) and anti-glyceraldehyde 3-phosphate dehydrogenase (GAPDH; red) were simultaneously measured in the 800- and the 700-nm channels, respectively, using the LI-COR Odyssey Infrared Western Blot Imaging System. (b) There was no significant difference in GAPDH-normalized PDE10A expression in the vehicle- and haloperidol-treated groups.