Figure 1 | Translational Psychiatry

Figure 1

From: Increased M1/decreased M2 signature and signs of Th1/Th2 shift in chronic patients with bipolar disorder, but not in those with schizophrenia

Figure 1

The M1 markers il6 (a) and ccl3 (b) differed among the three groups (P=0.009 and P=0.007, respectively; Kruskal–Wallis test, Bonferroni-corrected) and were upregulated in bipolar disorder patients (BD) compared with both healthy controls (HCs; P=0.03 and P=0.002, respectively) and schizophrenia patients (SCZ; P=0.024 and P=0.021, respectively; Mann–Whitney U-test, Bonferroni-corrected). The M2 markers ccl1 (c), ccl22 (d) and il10 (e) significantly differed among the groups (P=0.005, P=0.002 and P=0.009, respectively; Kruskal–Wallis test, Bonferroni-corrected) and were downregulated in individuals with BD compared with both HC (P=0.01, P=0.001 and P=0.09, respectively) and SCZ subjects (P=0.02, P=0.05 and P=0.011, respectively; Mann–Whitney U-test, Bonferroni-corrected).

Back to article page