Figure 2
From: Cerebellar Purkinje cell p75 neurotrophin receptor and autistic behavior
(a) Representative areas of a calbindin-stained sagittal section of cerebellum ( × 10; Bregma-6.84) from one wild-type and one Cre-loxP mouse, respectively, of three each examined. (b) Fraction of folium width occupied by Purkinje cell layer in wild-type versus Cre-loxP mice. (n=3 for each genotype; error bar=s.e.m.; NSD, wild type and Cre-loxP do not differ significantly from one another). (c, d) Number of neurites per μm2 area (c); visualized at × 20; n=3 for each genotype; error bar=s.e.m.; **P<0.025 relative to wild type and number of dot-like ‘nodes’ per 4 μm2 area (d); visualized at × 10; n=12 for each genotype; error bar=s.e.m.; **P<0.025 relative to wild type. (e) Number of short neurite branches off of long neurites/total number of neurites (that is, fraction of neurites that are short branches off of longitudinal neurites; n=3 for each genotype; visualized at × 20; error bar=s.e.m.; ***P<0.0005 relative to wild type).
