Figure 3 | Translational Psychiatry

Figure 3

From: Association of aberrant neural synchrony and altered GAD67 expression following exposure to maternal immune activation, a risk factor for schizophrenia

Figure 3

Analysis of PV immunoreactivity within PV-positive cells. (a) Analysis within the dorsal HPC revealed a reduction in GAD67 immunoreactivity relative to the ventral for MIA animals. (b) Analysis of PV immunoreactivity within the same dorsal HPC cells failed to produce an effect. (ci–iii) Micrographs illustrating immunohistochemistry staining of GAD67 (green) and PV (red). (c) The typical region of analysis within the ventral (i) and dorsal (ii) HPC depicted in white. (ciii) Increased magnification of the immunostaining showing double labeling GAD67+PV (yellow–red), and single GAD67 only (green) cells. GAD67, glutamic decarboxylase; HPC, hippocampus; MIA, maternal immune activation; PV, parvalbumin. *Significant (P<0.05) group by region interaction, n.s. (not significant).

Back to article page