Figure 3 | Translational Psychiatry

Figure 3

From: Label-free, live optical imaging of reprogrammed bipolar disorder patient-derived cells reveals a functional correlate of lithium responsiveness

Figure 3

Correlation of cellular BIND metrics to clinical features. (a) The four plots illustrate marginal means and 95% confidence intervals for the four cellular phenotypes identified using the BIND Scanner, with adjustment for age, sex and experiment. The asterisk denotes a significant difference in ΔPWV between BD Li Non-responders and BD Li Responders as indicated by Bonferroni corrected post hoc pairwise testing (P=0.02). (b) Marginal means and 95% confidence intervals for change in cell fraction, cell perimeter and PWV, with adjustment for change in cell count. (c) Results for change in PWV, adjusted as in b, by Alda score (degree of improvement with lithium) group. BD, bipolar disorder; PWV, peak wavelength value.

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