Table 1 Association results for rs16986890 with episodic memory performance measures in the BASE-II cohort

From: No association between CTNNBL1 and episodic memory performance

Trait

Mean (AA)

Mean (AG)

Mean (GG)

P-raw

P-adjusted

Beta

s.e.

SRFOBK (young)

0.6063

0.5927

0.7691

0.4984

1

−0.0983

0.1452

SRFOBK (old)

0.4643

0.4519

0.4483

0.0605

0.6655

−0.1592

0.0848

SRFO (young)

0.6033

0.5874

0.7896

0.4897

1

−0.1002

0.1450

SRFO (old)

0.4654

0.4536

0.4618

0.0761

0.8371

−0.1500

0.08453

SRFO_P1 (young)

0.8323

0.8557

0.9200

0.5249

1

0.0937

0.1474

SRFO_P1 (old)

0.6020

0.5928

0.5400

0.7670

1

−0.0253

0.08557

SRFO_P2 (young)

0.5691

0.5250

1.0000

0.3241

1

−0.1422

0.1441

SRFO_P2 (old)

0.2144

0.1859

0.1250

0.1437

1

−0.1231

0.08424

SRFO_P3 (young)

0.5622

0.5311

1.0000

0.7540

1

−0.0460

0.1467

SRFO_P3 (old)

0.2749

0.2420

0.3300

0.0756

0.8316

−0.1513

0.08513

SRBK (young)

0.5958

0.5861

0.7140

0.5893

1

−0.0789

0.1460

SRBK (old)

0.4676

0.4566

0.4417

0.1229

1

−0.1322

0.08572

SRBK_P1 (young)

0.7007

0.6848

1.0000

0.8337

1

−0.0307

0.1463

SRBK_P1 (old)

0.3773

0.3367

0.2500

0.0713

0.7843

−0.1566

0.08686

SRBK_P2 (young)

0.6483

0.6111

1.0000

0.4527

1

−0.1101

0.1466

SRBK_P2 (old)

0.2649

0.2440

0.2500

0.4167

1

−0.0693

0.08544

SRBK_P3 (young)

0.7922

0.7783

0.9200

0.7465

1

−0.0477

0.1475

SRBK_P3 (old)

0.6433

0.6136

0.6650

0.0559

0.6149

−0.1625

0.08471

Delay_2.5 h (young)

0.6928

0.6987

0.9200

0.9458

1

0.0099

0.1453

Delay_2.5 h (old)

0.6275

0.6393

0.5800

0.5163

1

0.0556

0.0886

Delay_1 week (young)

0.4563

0.4951

0.2400

0.4998

1

0.0982

0.1455

Delay_1 week (old)

0.2905

0.2544

0.2100

0.0061

0.0671

−0.2317

0.08444

Item–item (young)

0.6142

0.6385

1.0000

0.4917

1

0.0974

0.1416

Item–item (old)

0.5175

0.5234

0.6350

0.3906

1

0.0723

0.08412

Item–pair (young)

0.3555

0.2947

0.8700

0.2817

1

−0.1576

0.1463

Item–pair (old)

0.1709

0.2070

0.1800

0.1322

1

0.1288

0.08585

Pair–pair (young)

0.6349

0.5411

0.9300

0.0775

0.8525

−0.2570

0.1453

Pair–pair (old)

0.3998

0.3822

0.4850

0.6579

1

−0.0369

0.08321

PC1 (young)

−3.0145

−2.6460

−7.3921

0.4336

1

0.3117

0.3980

PC1 (old)

0.9629

1.2765

1.2932

0.0867

0.2601

0.2818

0.1644

PC2 (young)

0.03176

0.2000

0.1757

0.7019

1

0.0584

0.1526

PC2 (old)

−0.02567

0.06954

−0.07147

0.3976

1

0.0789

0.09339

PC3 (young)

−0.2131

−0.4852

1.4498

0.3237

0.9711

−0.1601

0.1621

PC3 (old)

0.05758

0.26661

0.8522

0.0213

0.0639

0.2054

0.08938

  1. Abbreviations: BASE-II, Berlin Aging Study II; P1, P2 and P3 are the first, second and third portion of the recall paradigms; P-adjusted, P-value after adjusting for multiple comparisons (see methods); P-raw, nominal P-value of association statistic; SRFOBK, combined accuracy of forward and backward serial recall tests; SRFO, accuracy of forward serial recall test; SRBK, accuracy of backward serial recall test.
  2. For more detailed descriptions of the tasks and traits, please see Supplementary Methods and Supplementary Table 1. For more details on the administration of these tests, see studies by Lewandowsky et al.,3 Li et al.17 and Papenberg et al.6 Phenotypic means of genotypes AA (1128–1173 old/373–377 young), AG (137–142 old/45–47 young) and GG (4 old/1 young) are shown in columns 2, 3 and 4, respectively.
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