Table 1 Characteristics of participants diagnosed with colorectal cancer according to 5-HTTLPR biallelic and triallelic genotype
Biallelic genotype | Triallelic genotype | |||||||
|---|---|---|---|---|---|---|---|---|
LL (n=266) | SL (n=412) | SS (n=128) | P-value | LALA (n=206) | L A L G , SLA (n=399) | LGLG, SLG, SS (n=188) | P-value | |
Age at diagnosis (years) | ||||||||
Mean (5%, 95%) | 66.4 (57,76) | 66.3 (57, 76) | 66.4 (57, 75) | 0.95 | 66.2 (58, 76) | 66.5 (57,76) | 66.2 (57,75) | 0.77 |
Sex, number of females (%) | 114 (43) | 171 (42) | 58 (45) | 0.74 | 86 (42) | 167 (42) | 83 (44) | 0.85 |
Educational level, n (%) | ||||||||
Basic | 49 (18) | 72 (17) | 29 (23) | 35 (17) | 71 (18) | 41 (22) | ||
Vocational | 152 (57) | 219 (53) | 67 (52) | 0.51 | 116 (56) | 217 (54) | 98 (52) | 0.79 |
High | 61 (23) | 118 (29) | 31 (24) | 52 (25) | 108 (27) | 48 (26) | ||
Unknown | 4 (2) | 3 (1) | 1 (1) | 3 (1) | 3 (1) | 1 (1) | ||
Cohabitation status at diagnosis, n (%) | ||||||||
Living alone | 84 (32) | 116 (28) | 37 (29) | 0.63 | 65 (32) | 119 (30) | 49 (26) | 0.47 |
Living with a partner | 182 (68) | 296 (72) | 91 (71) | 141 (68) | 280 (70) | 139 (74) | ||
Charlson comorbidity index score, n (%) | ||||||||
0 | 177 (67) | 268 (65) | 89 (70) | 0.67 | 135 (66) | 266 (66) | 126 (67) | 0.80 |
1 | 51 (19) | 71 (17) | 21 (16) | 42 (20) | 67 (17) | 32 (17) | ||
⩾2 | 38 (14) | 73 (18) | 18 (14) | 29 (14) | 66 (16) | 30 (16) | ||
Year of diagnosis (calendar year) | ||||||||
Mean (5%, 95%) | 2003.9 (1998, 2009) | 2004.1 (1998, 2009) | 2003.5 (1998, 2009) | 0.25 | 2003.9 (1999, 2009) | 2004.1 (1998, 2009) | 2003.5 (1998, 2009) | 0.08 |
Follow-up time (years) | ||||||||
Mean (5%, 95%) | 4.1 (0.1, 10.8) | 4.0 (0.1, 11.2) | 4.2 (0.1, 12.0) | 0.85 | 4.2 (0.1, 10.8) | 4.0 (0.1, 10.9) | 4.1 (0.1, 12.0) | 0.89 |
