Table 1 Sample size of each experimental condition and the sequence of different experiments in male offspring

From: Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model

 

Experiments

n6-SAL

n6-POL

n3-SAL

n3-POL

Age (days)

Neuroimaging

MRS

10

7

6

8

84–89

Behavioural tests (order of the tests)

Prepulse inhibition

13

9

8

8

98–105

 

Elevated plus maze

13

9

8

8

112–119

 

Open field test and amphetamine-induced locomotor activity

13

9

8

8

119–126

Physiological test

Body mass

13

9

8

8

133

Neurochemical test

Western blot

13

9

8

8

133

  1. Abbreviation: MRS, magnetic resonance spectroscopy; n6-POL, prenatal PolyI:C-exposed offspring treated with n-6 PUFA; n3-SAL, prenatal saline-exposed offspring treated with n-3 PUFA; n6-SAL, prenatal saline-exposed offspring treated with n6-polyunsaturated fatty acids (n-6 PUFA) control diet; PUFA, polyunsaturated fatty acids; Sal, saline.
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