Table 3 Association of differentially expressed genes with schizophrenia in the PGC sample

From: Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case–control sample of schizophrenia

Gene

Locus (hg19)

No. of markers in PGC_SCZ52

Best marker in PGC_SCZ52

P (best marker)

Locus-wide significance a

SF3B1

Chr2:198236697-198319771

318

rs6434928

1.5 × 10−11

4.7 × 10−9

FOXP1

Chr3:70983864-71653140

3431

rs7372960

1.2 × 10−7

0.00043

DLG2

Chr11:83146055-85358314

13 630

rs12294291

4.9 × 10−7

0.0067

VGLL4

Chr3:11577540-11782242

1508

chr3_11689216_D

1.4 × 10−5

0.021

ROBO1

Chr3:78626387-79837059

6944

rs188858898

7.4 × 10−5

0.52

AKAP5

Chr14:64912216-64961221

253

rs1980520

0.00023

0.057

PALM2

Chr9:112383067-112733756

2550

rs78341776

0.00033

0.83

SMAD2

Chr18:45339465-45477517

719

rs189158823

0.00045

0.32

CAMK4

Chr5:110539946-110840748

1685

rs117821127

0.00099

1

PRDM5

Chr4:121595928-121864013

1951

chr4_121723039_I

0.0010

1

SMURF2

Chr17:62520734-62678386

644

rs117024269

0.0014

0.92

CUL5

Chr11:107859407-107998488

753

chr11_107977411_I

0.0022

1

ARSG/WIPI1

Chr17:66235322-66473653

1395

rs149373128

0.0026

1

SPATA6

Chr1:48741043-48957880

1306

rs146859685

0.0028

1

TSLP

Chr5:110385777-110433722

291

rs79283270

0.011

1

MIA3

Chr1:222771443-222861351

448

rs9441835

0.011

1

ALB

Chr4:74249971-74307129

278

rs12651581

0.012

1

ADAMTS1

Chr21:28188605-28237728

350

rs181607589

0.013

1

KRT18

Chr12:53322654-53366685

270

rs113120949

0.014

1

FOXJ1

Chr17:74112414-74157380

267

rs117235875

0.014

1

  1. Abbreviation: PGC, Psychiatric Genetics Consortium.
  2. aP multiplied by the number of markers at each locus; rs6434928, rs7372960 and rs12294291 remain significantly associated at P<0.05 when correcting for all 38 991 markers from the 20 tested loci.