Table 1 CORT-mediated (50 mg kg⁻¹, 21 days s.c.), altered miRNAs in rat prefrontal cortex and their characteristics

From: Chronic corticosterone-mediated dysregulation of microRNA network in prefrontal cortex of rats: relevance to depression pathophysiology

miRNAs	Accession no.	Fold change	P-value	Regulation	Chromosomal location (Rat)	Seed sequence	Transcriptional unit
miR-19b	MIMAT0000788	1.284078291	0.015148	↑	chr15: 103641487-103641573 [+] chrX: 140167226-140167321 [−]	5′-GUGCAAA-3′	Intergenic, intergenic
miR-29c	MIMAT0000803	1.565815431	0.004636	↑	chr1: 39612916-39613003 [+] chr13: 118329978-118330065 [+]	5′-AGCACCA-3′	Exonic, exonic
miR-101a	MIMAT0000823	1.594450158	0.028947	↑	chr5: 124050126-124050200 [−]	5′-ACAGUAC-3′	Exonic
miR-124	MIMAT0000828	1.768260098	0.000853	↑	chr3: 180116126-180116212 [+] chr15: 51712751-51712835 [+] chr2: 122049028-122049136 [+]	5′-AAGGCAC-3′	Intergenic, intergenic, intergenic
miR-137	MIMAT0000843	1.394684534	0.009357	↑	chr2: 239707763-239707864 [+]	5′-UAUUGCU-3′	Intergenic
miR-153	MIMAT0000855	2.328177683	0.015395	↑	chr6: 154028732-154028818 [+]	5′-UGCAUAG-3′	Intronic
miR-181a	MIMAT0000858	1.443247107	0.034332	↑	chr3: 28374769-28374885 [+] chr13: 59986075-59986174 [+]	5′-ACAUUCA-3′	Intronic, exonic
miR-181c	MIMAT0000857	1.731680672	0.012072	↑	chr19: 36267311-36267416 [−]	5′-ACAUUCA-3′	Intergenic
miR-203	MIMAT0000876	1.39812046	0.033212	↑	chr6: 145714633-145714729 [+]	5′-UGAAAUG-3′	Exonic
miR-218	MIMAT0000888	1.285324379	0.000235	↑	chr10: 20303158-20303267 [+] chr14: 66955494-66955603 [−]	5′-UGUGCUU-3′	Intronic, exonic, intronic
miR-324-5p	MIMAT0000553	1.412569727	0.049794	↑	chr10: 56366245-56366327 [+]	5′-GCAUCCC-3′	Exonic, intronic
miR-365	MIMAT0001549	1.279026214	0.035465	↑	chr10: 64570072-64570157 [−]	5′-AAUGCCC-3′	Intergenic
miR-409-5p	MIMAT0003204	1.497710118	0.047871	↑	chr6: 143055776-143055852 [+]	5′-GGUUACC-3′	Exonic
miR-582-5p	MIMAT0012833	1.810050564	0.008875	↑	chr2: 59928607-59928687 [+]	5′-UACAGUU-3′	Intronic
miR-29a	MIMAT0000802	1.594299491	0.003691	↑	chr4: 58099674-58099761 [−]	5′-AGCACCA-3′	Exonic
miR-30e	MIMAT0000805	1.380416302	0.02323	↑	chr5: 143497752-143497843 [−]	5′-GUAAACA-3′	Intronic
miR-721	No report	1.691847218	0.037392	↑	Not reported	5′-AGUGCAA-3′	Not reported
miR-699	No report	2.007193854	0.008792	↑	Not reported	Not reported	Not reported
miR-146a	MIMAT0000852	0.603748944	0.006804	↓	chr10: 28806739-28806833 [−]	5′-GAGAACU-3′	Intergenic
miR-200c	MIMAT0000873	0.114793637	0.016703	↓	chr4: 224254382-224254450 [−]	5′-AAUACUG-3′	Exonic
miR-351	MIMAT0000608	0.654310843	0.025434	↓	chrX: 152774513-152774593 [+] chrX: 153212230-153212310 [+]	5′-CCCUGAG-3′	Intergenic, intergenic
miR-155	MIMAT0030409	0.526008585	0.020242	↓	chr11: 27810358-27810422 [+]	5′-UAAUGCU-3′	Intergenic
miR-678	MIMAT0012857	0.679476805	0.038127	↓	chr20: 15366762-15366844 [+]	5′-UCUCGGG-3′	Exonic
miR-764-5p	MIMAT0012854	0.66665086	0.032063	↓	chrX: 118264668-118264775 [+]	5′-GUGCUCA-3′	Intergenic
miR-135a-3p	MIMAT0004732	0.738454042	0.02441	↓	chr7: 32974076-32974175 [−]	5′-AUGGCUU-3′	Intergenic

Abbreviations: CORT, corticosterone; miR, microRNA.

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Table 1 CORT-mediated (50 mg kg⁻¹, 21 days s.c.), altered miRNAs in rat prefrontal cortex and their characteristics

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