Table 2 Results from the meta-analysis for smoking cessation stratified by different data sets

From: The significant association of Taq1A genotypes in DRD2/ANKK1 with smoking cessation in a large-scale meta-analysis of Caucasian populations

Data set of meta-analysis (A1A1+A1A2 vs A2A2)

Cohorts (n)

Sample size (N)

Estimate of heterogeneity

Fixed-effects model

Random-effects model

Ba

   

I2(%)

P (Q)

Pooled OR

95% CI

P (Z)

Pooled OR

95% CI

P (Z)

P (B)

Cross-sectional data setb

10

4457

53.8

0.02

1.12

0.99–1.27

0.07

1.03

0.81–1.30

0.84

0.35

Cross-sectional data setc

5

3737

57.0

0.05

1.19

1.04–1.36

0.01

1.12

0.87–1.45

0.38

0.62

Cross-sectional data setd

4

3378

0

0.97

1.27

1.10–1.46

0.001

1.27

1.10–1.46

0.001

0.50

Longitudinal data sete

14

6694

11.4

0.33

1.20

1.06–1.36

0.003

1.20

1.05–1.37

0.007

0.87

Longitudinal data setf

13

6469

6.1

0.39

1.18

1.04–1.34

0.01

1.18

1.03–1.34

0.01

0.62

Combined data setg

24

11 151

33.9

0.055

1.16

1.06–1.27

0.0008

1.13

1.00–1.27

0.04

0.40

Combined data seth

18

10 206

23.0

0.18

1.18

1.08–1.30

3 × 10−4

1.16

1.04–1.30

0.009

0.44

Combined data seti

17

9847

0.0

0.63

1.22

1.11–1.34

3.9 × 10−5

1.22

1.11–1.34

3.9 × 10−5

0.53

Combined data setj

4

945

72.8

0.01

0.97

0.72–1.32

0.86

1.05

0.56–1.96

0.88

0.68

  1. Abbreviations: CI, confidence interval; OR, odds ratio.
  2. aEgger regression test for publication bias.
  3. bAnalysis of cross-sectional data extracted from all the cross-sectional surveys.
  4. cAnalysis of cross-sectional data based on Caucasian population.
  5. dAnalysis of cross-sectional data based on Caucasian population without the data of the Gordiev study.
  6. eAnalysis of longitudinal data extracted from all the longitudinal studies.
  7. fAnalysis of longitudinal data extracted based on Caucasian population.
  8. gAnalysis of combined data extracted from both the cross-sectional surveys and the longitudinal studies.
  9. hAnalysis of combined data based on Caucasian population.
  10. iAnalysis of combined data based on Caucasian population without the data of the Gordiev study.
  11. jAnalysis of combined data based on Asian population.