Table 3 Results of meta-analysis for the association between Taq1A A1/* genotypes and smoking cessation across combined studies based on predominantly Caucasian origin with the Gordiev study

From: The significant association of Taq1A genotypes in DRD2/ANKK1 with smoking cessation in a large-scale meta-analysis of Caucasian populations

Study name

Sample size

% Weight

Odds ratio

95% Confidence interval

Z-test

P-value

Noble et al.17

172

2.13

1.26

0.66–2.39

0.70

0.483

Bierut et al.20

954

12.26

1.23

0.94–1.61

1.51

0.130

Lerman et al.38

425

2.33

1.14

0.62–2.10

0.41

0.680

Cinciripini et al.53

134

4.86

1.54

1.01–2.35

1.99

0.046

Yudkin et al.18, 36, 37

752

4.11

0.84

0.53–1.33

−0.76

0.448

Berlin et al.40

595

6.32

1.38

0.95–2.00

1.70

0.090

Morton et al.15

2123

28.16

1.27

1.07–1.52

2.68

0.007

Swan et al.43

323

3.51

1.53

0.93–2.52

1.67

0.095

Ton et al.43, 51

586

3.99

1.12

0.70–1.79

0.47

0.635

David et al.39

291

2.31

0.88

0.48–1.63

−0.40

0.687

Wernicke et al.19

129

1.49

1.51

0.70–3.24

1.05

0.296

Munafo et al.29, 41

804

3.74

1.05

0.65–1.71

0.21

0.834

Styn et al.48

881

7.56

1.46

1.04–2.05

2.17

0.030

Breitling et al.54

562

2.66

0.68

0.38–1.21

−1.31

0.190

Stapleton et al.52

419

5.76

1.06

0.72–1.57

0.30

0.767

Wilcox et al.55

76

0.56

2.18

0.63–7.63

1.22

0.221

Tashkin et al.50

621

8.25

1.14

0.82–1.57

0.77

0.440

Pooled analysis

9847

100.00

1.22

1.10–1.33

4.11

3.9 × 10−5

  1. Notes: test for heterogeneity: χ2=13.6, df=16 (P=0.63), I2=0%. Test for overall effect under both fixed-effects and random-effects model: Z=4.03 (P=3.9 × 10−5).
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