Table 2 HLS1 associations with schizophrenia features

From: DUF1220 copy number is associated with schizophrenia risk and severity: implications for understanding autism and schizophrenia as related diseases

Phenotype measure

Beta

s.e.

P-value

SAPS: total populationa

−0.022

0.01

0.0227

SAPS: childhood onset

−0.03

0.03

0.28

SAPS: adolescent onset

0.003

0.017

0.83

SAPS: adult onset

−0.038

0.013

0.00361

SANS: malesb

0.027

0.017

0.119

  1. Abbreviations: SANS, scale for the assessment of negative symptoms; SAPS, scale for the assessment of positive symptoms.
  2. Results from regression analyses of DUF1220 subtype HLS1 copy number versus positive symptom score (SAPS), negative symptom score (SANS) stratified by age of onset. The stratified population description is available in Supplementary Table 2.
  3. P-values meeting statistical significance (<0.05) are in bold.
  4. aHLS1 versus SAPS model includes SANS and age as covariates; age-specific models include SANS as a covariate.
  5. bHLS1 versus SANS model includes SAPS as covariate.
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