Figure 2
From: Absence of IFNγ promotes hippocampal plasticity and enhances cognitive performance
The structure of the dorsal but not the ventral hippocampus is altered in IFNγ KO mice. Stereological estimations of volumes of the (a) dorsal DG, CA3 and CA1; and of the (d) ventral DG, CA3 and CA1. (b) Stereological estimations of volumes from CA1 strata oriens, pyramidale and radiatum. (e) Outlining of the different subareas: DG, CA3 and CA1—diagrams were adapted from the Paxinos mouse brain atlas,40 corresponding brain slices were stained with Giemsa. Stereological estimations of cell numbers on the dorsal (c) and ventral (f) hippocampus (strata pyramidale for CA1 and CA3 and granule cell layer for DG). IFNγ KO n=5 and WT=5. Error bars denote s.e.m.; *P<0.05. DG, dentate gyrus; IFNγ, interferon-γ; KO, knockout; WT, wild type.
