Figure 3
From: Absence of IFNγ promotes hippocampal plasticity and enhances cognitive performance
Neurogenesis is increased in the DG of the dorsal hippocampus of IFNγ KO mice. Photomicrograph depicts Ki-67 (red) and PSA-NCAM (green) double staining in the DG SGZ from WT (a) and IFNγ KO (b). Graph displays the percentage of newly born neurons (Ki-67+ cells that express PSA-NCAM+) by the total proliferating cells (Ki-67+) for assessing neurogenesis (differentiation) in the DG SGZ of the dorsal hippocampus (c). IFNγ KO n=3 and WT=3. Scale bar, 30 μm. Error bar denotes s.e.m. *P<0.05. DG, dentate gyrus; IFNγ, interferon-γ; KO, knockout; PSA-NCAM, polysialic acid-NCAM antibody; SGZ, subgranular zone; WT, wild type.
