Figure 1 | Translational Psychiatry

Figure 1

From: Dysfunction in the coagulation system and schizophrenia

Figure 1

(a) Plasminogen and tPA must bind to the heterotetramer formed by two molecules of p11 and two molecules of annexin A2 to generate plasmin. Plasmin dissolves the fibrin net. (b). Antiphospholipid antibodies and homocysteine inhibit tPA-induced proteolysis and fibrinolysis. tPA, tissue plasminogen activator.

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